Professor, Cell and Molecular Biology
Core, Driskill Graduate Training Program in Life Sciences
Core, Medical Scientist Training Program
Core, Northwestern University Interdepartmental Neuroscience PhD Program (NUIN)
Our research focuses on molecular and cellular mechanisms of Alzheimer's disease. In particular, we investigate the beta-secretase enzyme BACE1, which initiates the production of the beta-amyloid peptide that plays a central early role in the pathogenesis of Alzheimer's. We use a combination of biochemical, cell culture and animal model approaches to investigate the role of BACE1 in health and disease.
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