Yong Shen, Ph.D.

Research Interests:

The mechanisms of neurodegenerative diseases

Animal models of neurodegenerative diseases

Early diagnosis and novel technologies development of neurodegenerative diseases

Drug discoveries and therapeutic strategies in neurodegenerative diseases

Awards and Honors:

Distinguished professor of the Chang Jiang Scholars Program

Zenith Fellows Award, Alzheimer’s Association

Outstanding Contributor to Alzheimer Research

Selected Publications:

Nature Medicine, 9(1): 3-4.

PNAS, 101(10), 3632-3637.

Journal of Neuroscience, 28(7):1760-1771.

JAMA Psychiatry, 64(6):718-2.

Journal of Cell Biology, 178(5): 829-841

Neurology. 82(19): 1707-1715.

Representative Research Findings:

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

TNFR signalling contributes to AD pathology