Xiaoyuan Song, PhD

EDUCATION AND RESEARCH EXPERIENCE 

2012.12-present　　Professor, Youth Thousand Talents Program, University of Science & Technology of China,
2006-2012　　　　　Postdoctoral fellow, University of California, at San Diego, CA, USA

1999-2006　　　　　Ph.D, University of Rochester, USA

1996-1999　　　　　M.S, Beijing Normal University, China

1992-1996　　　　　B.A, Biology, Beijing Normal University, China

RESEARCH INTERESTS

1. Roles of three-dimensional transcriptional regulation of lncRNA and genome structure in brain aging

2. Transcriptional regulation of lncRNA and chromatin interaction in spermatogenesis

3.　Function and molecular mechanism of meiosis specific genes

REPRESENTATIVE PUBLICATIONS

1. Muhammad A, Waheed R, Khan NA, Jiang H, Song X, piRDisease v1.0: a manually curated database for piRNA associated diseases. Database (Oxford). 2019 Jan 1;2019. pii: baz052.

2.  Wang F, Ren D, Liang X, Ke S, Zhang B, Hu B, Song X, Wang X, A long  noncoding RNA cluster-based genomic locus maintains proper development  and visual function. Nucleic Acids Res. 2019 Jul 9;47(12):6315-6329

3. Mamun MA, Mannoor K, Cao J, Qadri F, Song X, SOX2 in Cancer Stemness: Tumor Malignancy and Therapeutic Potentials. J Mol Cell Biol. 2018 Dec 5.

4. Xu Q, Wang R, Ghanam AR, Yan G, Miao W, Song X, The key role of CYC2 during meiosis in Tetrahymena thermophila. Protein Cell. 2016 Apr;7(4):236-249.

5.  Lü M., Tian H., Cao Y., He X., Chen L., Song X., Ping P., Huang H., Sun  F. Downregulation of miR-320a/383-sponge-like long non-coding RNA  NLC1-C (narcolepsy candidate-region 1 genes) is associated with male  infertility and promotes testicular embryonal carcinoma cell  proliferation. Cell Death Dis. 2015, doi: 10.1038/cddis.

6.  Li W., Hu Y., Oh S., Ma Q., Merkurjev D., Song X., Zhou X., Liu Z.,  Tanasa B., He X., Chen AY., Ohgi K., Zhang J., Liu W., Rosenfeld MG.  Condensin I and II Complexes License Full Estrogen Receptor α-Dependent  Enhancer Activation.Mol Cell. 2015, 59(2):188-202.

7. Cao J., Luo Z., Cheng Q., Xu Q., Zhang Y., Wang F., Wu Y., Song X.*. Three-dimensional regulation of transcription. Protein & Cell. 2015, 6(4):241-53.

8.  Zhang F., Tanasaa B. #, Merkurjev D. #, Lin C. #, Song X., Li W, Tan Y,  Liu Z., Zhang J., Ohgi KA., Kronesa A., Skowronska-Krawczyka D.,  Rosenfeld MG. Enhancer-bound LDB1 regulates a corticotrope  promoter-pausing repression program. PNAS. 2015, 112(5):1380-5.

9.  Wang X.* and Song X.*, Glass C.K., and Rosenfeld M.R. The long arm of  long non-coding RNAs: Roles as sensors regulating gene transcriptional  programs. Cold Spring Harb Perspect Biol. 2011 doi:  10.1101/cshperspect.a003756. *Equal contributors.A chapter in《The RNA World》, 4th edition.

E-mail: songxy@ustc.edu.cn

Phone: 0551-63607752